I know one way he responds.
He uses His Word. The Living Word. The Good Book. The Bible.
There were a lot of times when scripture was the only thing to pull me out of the dumps of my depression. I remember being balled up on the floor, crying, and repeating Romans 8:28. Believing what that scripture said gave me hope to keep going, and I started reading the Bible like it was a letter to me from God.
This devotional is like my e-introduction to God and his responses. I hope it encourages you as much as it has encouraged me.